外星人入侵，打断了一场告别单身派对。两名儿时好友只好再度合体，变身当年的超猛雷射枪搭档，出手反击。
因为一起天然气爆炸事件，让古董店老板唐古跌入人生谷底，挚爱的妻子和弟弟同时殒命，唐古意外发现古董店新收的老钟能够带他回到爆炸前的一刻，由此上演了一出生死时速，然而这起“事故”并非如他所想的那样简单。
威尼斯，这个古老绵城市，在未来的某一天不幸地被大水侵蚀。政府组织了一支突击队准备进行救援工作，奇怪的是，此次救援工作却成了一次地下战争在地下通道里，发现了一群怪物，更严惩的是突击队员们依个遭到残害，结果， 科学家们在研究中发现，一种奇怪的现象在隐隐地影响着这座城市。就这样，整个城市的人们都面临着危机，和这种奇怪而又可怕的东西展开了激烈的斗争……
The boisterous, arrogant professor Challenger, a reputed biologist and anthropologist, dares the London Zoological Society to mount an expedition to verify his spectacular claim, without physical proof, that his previous expedition to the Amazonian basin found live dinosaurs. Apart from him and his 'socialite' counterpart, professor Summerlee, it consists of experienced discoverer Lord Roxbury, the young reporter Ed Malone -who got publicly struck down with Challenger's umbrella at his arrival- and Jennifer Holmes, Malone's news agency's boss's daughter, essentially as conditions for putting up the money. In Brazil they are joined by Jennifer's brother David and local 'guide' Manuel Gomez. They soon discover the dinosaurs are real and dangerous, like giant spiders, but loose their helicopter and thus are desperate for a way down from the isolated plateau. They learn Roxbury knew about the fate of Burton White, an explorer whose diary they find, thus presume to be dead, in search of diamonds, and confirmation of the local tribe being the lethal guardians of the plateau's secrets, but also get surprising help...
