4400人被未来世界的人带走又送回来，一年后，世界发生了巨大的变化。科利尔已经关掉了Arcadia Estates ，还有他的住宅，为这4400人建起了避难所，同时准备开“4400人中心”，在这儿，其他人可以深入到这4400人当中，自己去发掘4400人的奥秘。 世人对4400人甚感好奇，于是关于他们的神秘能力的流言四处传播，公众态度分为两种，一种是包容他们，一种是畏惧他们。当4400人努力重新开始他们“被打断的生活”时，每个人都会在即将发生的事件中扮演关键角色…那些决定人类命运的事件。
Ally McBeal Season 4 Season 4, Episode 1: Sex, Lies and Second Thoughts Season 4, Episode 2: Girls' Night Out Season 4, Episode 3: Two's a Crowd Season 4, Episode 4: Without a Net Season 4, Episode 5: The Last Virgin Season 4, Episode 6: Tis the Season Season 4, Episode 7: Love on Holiday Season 4, Episode 8: The Man with the Bag Season 4, Episode 9: Reasons to Believe Season 4, Episode 10: The Ex-Files Season 4, Episode 11: Mr. Bo Season 4, Episode 12: Hats Off to Larry Season 4, Episode 13: Reach Out and Touch Season 4, Episode 14: Boy's Town Season 4, Episode 15: Falling Up Season 4, Episode 16: The Getaway Season 4, Episode 17: The Pursuit of Unhappiness Season 4, Episode 18: The Obstacle Course Season 4, Episode 19: In Search of Barry White Season 4, Episode 20: Cloudy Skies, Chance of Parade Season 4, Episode 21: Queen Bee Season 4, Episode 22: Home Again Season 4, Episode 23: The Wedding
这部剧集由《愚人善事》（My Name Is Earl）创作人Greg Garcia打造。故事讲述23岁的Jimmy Chance与一个女人一夜风流之后，对方竟生下了他的女儿。更糟的是，这个女人随后被判处死刑，Jimmy必须独自抚养这个孩子。
